Research Thread
Translational Neuroinformatics
Computational infrastructure linking cohorts, biomarkers, cognition, and brain health outcomes.
Translational neuroinformatics connects clinical, cognitive, biological, and computational systems so that research outputs can move across scales and communities.
This thread carries the largest share of the publication record: cohort studies, harmonization work, and biomarker analyses that only become comparable once the underlying data infrastructure is made consistent.
How do cohort data, biomarkers, and cognitive measures become comparable enough to answer translational questions?

Development of a refined harmonization approach for longitudinal cognitive data in people with HIV
Journal of Clinical Epidemiology

International application of an optimized harmonization approach for longitudinal cognitive data in people with HIV
Journal of Clinical Epidemiology
Objectives: We previously developed a refined longitudinal data harmonization method to address the challenge of nonoverlapping cognitive tests across cohorts, successfully harmonizing data …

Biopsychosocial phenotypes in people with HIV in the CHARTER cohort
Brain Communications

Heterogeneity in neurocognitive change trajectories among people with HIV starting antiretroviral therapy in Rakai, Uganda
Journal of neurovirology
Considerable heterogeneity exists in patterns of neurocognitive change in people with HIV (PWH). We examined heterogeneity in neurocognitive change trajectories from HIV diagnosis to 1–2 …